Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.
1. Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation. Moursy A, Allain FH, Cléry A, et al. Nucleic Acids Res. 42(10), 6659-72, (2014)
2. Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity. Mao Y, Sarhan D, Steven A, et al. Clin. Cancer Res. 20(15), 4096-106, (2014)